Once the Renaissance residence of the court of Pius IV and since 1929, after the signing of the Lateran Pacts, the seat of the Embassy of the Italian Republic to the Holy See.
The palace was built in the 16th century by Pius IV, born Gian Angelo Medici. After being owned for a long time by the Colonna family, it was purchased by Cavaliere Giuseppe Balestra, and later by the antiquarian Ugo Jandolo, before being chosen by Benito Mussolini in 1929 to house the Italian diplomatic representation to the Holy See.
Every year, the signing of the Lateran Pacts is celebrated in its halls, a ceremony attended by the highest offices of the Italian State, the President of the Republic, the Presidents of the Senate, the Chamber of Deputies and the Constitutional Court, the President of the Council of Ministers, and the highest hierarchies of the Holy See and the Italian Bishops' Conference.
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